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Alessandro Poffe Selected Research

SB-616234-A

6/2006Characterisation of the selective 5-HT1B receptor antagonist SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): in vivo neurochemical and behavioural evidence of anxiolytic/antidepressant activity.

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Alessandro Poffe Research Topics

Disease

2Nausea
07/2014 - 11/2013
2Vomiting
07/2014 - 11/2013
1Pica (Geophagia)
07/2014
1Pneumonia (Pneumonitis)
07/2014
1Chronic Obstructive Pulmonary Disease (COPD)
07/2014
1Major Depressive Disorder (Major Depressive Disorders)
11/2013
1Sleep Wake Disorders
09/2011
1Sleep Initiation and Maintenance Disorders (Insomnia)
09/2011
1Hypothermia
06/2006
1Mood Disorders (Mood Disorder)
06/2006

Drug/Important Bio-Agent (IBA)

1RoflumilastIBA
07/2014
1RolipramIBA
07/2014
1Phosphodiesterase 4 InhibitorsIBA
07/2014
1Aprepitant (Emend)FDA Link
11/2013
1orvepitantIBA
11/2013
1Orexin ReceptorsIBA
09/2011
1OrexinsIBA
09/2011
15-HT1B Serotonin ReceptorIBA
06/2006
1SB-616234-AIBA
06/2006

Therapy/Procedure

1Drug Therapy (Chemotherapy)
11/2013
1Therapeutics
06/2006